Show simple item record

dc.contributor.authorWong McClure, Roy
dc.contributor.authorRamírez Salas, Elenita
dc.contributor.authorMora Brenes, Nury
dc.contributor.authorAguero Sandí, Lorena
dc.contributor.authorMorera Sigler, Maritza
dc.contributor.authorBadilla Vargas, Xiomara
dc.contributor.authorHernández de Merzerville, Marcela
dc.contributor.authorO’Shea, Michele
dc.contributor.authorBryce, Elizabeth
dc.date.accessioned2017-02-10T16:36:18Z
dc.date.available2017-02-10T16:36:18Z
dc.date.issued2013
dc.identifier.urihttp://hdl.handle.net/20.500.11764/630
dc.descriptionARTICULOes_ES
dc.description.abstractIntroduction: The C. difficile BI/NAP 1 hyper virulent strain has been responsible for the nosocomial outbreaks in several Countries. The present study describes the infection control strategies utilized to achieve outbreak control as well as the factors associated with a C. difficile BI/NAP 1 hyper virulent strain outbreak in Costa Rica. Methodology: A descriptive analysis of the C. difficile outbreak was completed for the period of January 2007 to December 2010 in one affected hospital. An unmatched case-control study was subsequently performed to evaluate the association of exposure factors with C. difficile infection. Results: The pattern of the outbreak was characterized by a sharp increase in the incidence rate during the initial weeks of the outbreak, which was followed by a reduction in the incidence curve as several infection control measures were implemented. The C. difficile BI/NAP1 infection was associated with the prescription of antibiotics, in particular levofloxacin (OR: 9.3; 95%CI: 2.1-40.2), meropenem (OR: 4.9, 95%CI: 1.0-22.9), cefotaxime (OR: 4.3, 95%CI: 2.4-7.7), as well as a medical history of diabetes mellitus (OR: 2.9, 95%CI: 1.5-5.8). Conclusions: The infection control strategies implemented proved to be effective in achieving outbreak control and in maintaining the baseline C. difficile incidence rate following it. The reported C. difficile outbreak was associated with the prescription of broad-spectrum antibiotics and a medical history of diabetes.es_ES
dc.description.sponsorshipLos autoreses_ES
dc.language.isoenes_ES
dc.relation.ispartofseriesJ Infect Dev Ctries;7(12):914-921
dc.subjectCLOSTRIDIUMes_ES
dc.subjectCOSTA RICAes_ES
dc.subjectENTEROCOLITISes_ES
dc.subjectINSTITUCIONES DE SEGURIDAD SOCIALes_ES
dc.titleLong term effect of infection control practices and associated factors during a major Clostridium difficile outbreak in Costa Ricaes_ES
dc.title.alternativeOutbreakes_ES
dc.typeArticlees_ES


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record